Glanzmann's thrombasthenia physical examination

Glanzmann's thrombasthenia
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Omer Kamal, M.D.[2], Niyousha Danesh, MD-MPH

Overview

Patients with Glanzmann's thrombasthenia may be asymptomatic, or they could manifest mucosal bleeding, ecchymoses, petechiae and purpura or current bleeding on physical exam.

Physical examination

Appearance of the Patient

• Patient appears well in the absence of severe hemorrhage
• Patient appears ill in the persistent bleeding.

Vital Signs

• May haveTachycardia, depends on the severity of the bleeding
• May haveTachypnea depends on severity of the bleeding

Skin

• Cyanosis
• Pallor
  • Secondary to anemia
• Ecchymoses,petechiae and purpura
  • Secondary to thrombocytopenia

HEENT

• Evidence of trauma
• Pale conjunctiva
• Epistaxis
• Palatal petechiae
• Gingival or other oral cavity bleeding

Neck

No specific signs

Lungs

• Commonly normal lung sounds

Heart

• Commonly normal heart sounds

Abdomen

The spleen is usually non palpable

Neuromuscular

• Patient is usually oriented to persons, place, and time
• Glasgow coma scale is normally 15 / 15 but may may present loss of consciousness in severe fatal hemorrhage episodes

Gallery

Extremities

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  Glanzmann’s trombastenia. With permission from Dermatology Atlas.

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  Glanzmann’s trombastenia. With permission from Dermatology Atlas.

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  Glanzmann’s trombastenia. With permission from Dermatology Atlas.

• 

  Glanzmann’s trombastenia. With permission from Dermatology Atlas.

• 

  Glanzmann’s trombastenia. With permission from Dermatology Atlas.

• 

  Glanzmann’s trombastenia. With permission from Dermatology Atlas.

• 

  Glanzmann’s trombastenia. With permission from Dermatology Atlas.

• 

  Glanzmann’s trombastenia. With permission from Dermatology Atlas.

References