Myelofibrosis MRI

	Myelofibrosis Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Myelofibrosis from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X-ray
Echocardiography and Ultrasound
CT scan
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Myelofibrosis MRI On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Myelofibrosis MRI All Images X-rays Echo and Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Myelofibrosis MRI
CDC on Myelofibrosis MRI
Myelofibrosis MRI in the news
Blogs on Myelofibrosis MRI
Directions to Hospitals Treating Myelofibrosis
Risk calculators and risk factors for Myelofibrosis MRI

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

MRI may be helpful in the diagnosis of myelofibrosis. Findings on MRI suggestive of myelofibrosis include diffuse decrease in bone marrow signal intensity.

MRI may be helpful in the diagnosis of myelofibrosis and can be useful in evaluating the stage and the progression of disease.
Findings on MRI suggestive of myelofibrosis include:

Diffuse decrease in bone marrow signal intensity.^[1]^[2]^[3]
Very low, mainly homogeneous signal on both T1- and T2-weighted images^[4]
Foci of extramedullary hematopoiesis (EMH) involving the spine manifest as heterogeneous and predominantly hyperintense masses
Foci of intracranial extramedullary hematopoiesis (EMH) manifest as masses of variable signal intensity^[5]

_{MR images demonstrate diffuse decrease bone marrow signal intensity in this patient with myelofibrosis.^[6]}

↑ Radiographic features of myelofibrosis. Radswiki. Radiopaedia 2016. http://radiopaedia.org/cases/myelofibrosis-1. Accessed on March 14, 2016
↑ Ueda F, Takashima T, Suzuki M, Kadoya M (1994). "MR diagnosis of myelofibrosis". Radiat Med. 12 (3): 135–7. PMID 7972898.
↑ Lanir A, Aghai E, Simon JS, Lee RG, Clouse ME (1986). "MR imaging in myelofibrosis". J Comput Assist Tomogr. 10 (4): 634–6. PMID 3734203.
↑ Guermazi A, de Kerviler E, Cazals-Hatem D, Zagdanski AM, Frija J (1999). "Imaging findings in patients with myelofibrosis". Eur Radiol. 9 (7): 1366–75. doi:10.1007/s003300050850. PMID 10460376.
↑ Koch BL, Bisset GS, Bisset RR, Zimmer MB (June 1994). "Intracranial extramedullary hematopoiesis: MR findings with pathologic correlation". AJR Am J Roentgenol. 162 (6): 1419–20. doi:10.2214/ajr.162.6.8192010. PMID 8192010.
↑ Image courtesy of Radswiki. Radiopaedia (original file here). Creative Commons BY-SA-NC