Epilepsy natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.

Overview

Natural History, Complications, and Prognosis

Natural History

  • The symptoms of (disease name) usually develop in the first/ second/ third decade of life, and start with symptoms such as ___.
  • The symptoms of (disease name) typically develop ___ years after exposure to ___.
  • If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].

Complications

  • Common complications of epilepsy include:
    • Submersion Injury[1]
    • Burns[2]
    • Fractures[3]
    • Head injury
    • Soft tissue injury
    • Dental injury
    • Motor vehicle accidents

Prognosis

  • Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [--]%.
  • Depending on the extent of the [tumor/disease progression] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
  • The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
  • [Subtype of disease/malignancy] is associated with the most favorable prognosis.
  • The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.

References

  1. Buck D, Baker GA, Jacoby A, Smith DF, Chadwick DW (April 1997). "Patients' experiences of injury as a result of epilepsy". Epilepsia. 38 (4): 439–44. PMID 9118849.
  2. van den Broek M, Beghi E (January 2004). "Morbidity in patients with epilepsy: type and complications: a European cohort study". Epilepsia. 45 (1): 71–6. PMID 14692910.
  3. Pack AM, Olarte LS, Morrell MJ, Flaster E, Resor SR, Shane E (April 2003). "Bone mineral density in an outpatient population receiving enzyme-inducing antiepileptic drugs". Epilepsy Behav. 4 (2): 169–74. PMID 12697142.

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