Breast lumps other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]

Other Diagnostic Studies

The only certain method to approve the presence of breast malignancy is breast lump biopsy ^[1]

There are three types of biopsy:

Core needle biopsy^[1]

Ultrasound guided-core needle biopsy^[3]
- The needle is guided by use of ultrasound and patient lies on back or side
- Highly sensitivity and specificity
- Choice method for breast tissue sampling
Stereotactic-guided core-needle biopsy
- The needle is guided by use of x-ray and computer and patient lie on stomach
- Choice method for mammograohically suspicious breast lumps which are occult in ultrasound^[4]
MRI-guided core-needle biopsy
- The needle is guided by Magnetic resonance imaging
Freehand core-needle biopsy
- Usually used for breast lumps which can be felt by hand on breast tissue

Open surgical biopsy^[1]

Perform under general anesthesia
If core-needle biopsy is unavailable due to location of breast lump, open surgical biopsy is required
In patients with high risk of cancer is recommended
1-2 inch cut on breast tissue for breast lump removal

↑ ^1.0 ^1.1 ^1.2 John M. Eisenberg Center for Clinical Decisions and Communications Science. Having a Breast Biopsy: A Review of the Research for Women and Their Families. 2016 May 26. In: Comparative Effectiveness Review Summary Guides for Consumers [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2005-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK368364/
↑ Casaubon JT, Regan JP. Breast Masses, Fine Needle Aspiration. [Updated 2018 Oct 27]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470268/
↑ Yeow KM, Lo YF, Wang CS, Chang HK, Tsai CS, Hsueh C (2001). "Ultrasound-guided core needle biopsy as an initial diagnostic test for palpable breast masses". J Vasc Interv Radiol. 12 (11): 1313–7. PMID 11698631.
↑ Ward ST, Shepherd JA, Khalil H (2010). [htps://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20074953 "Freehand versus ultrasound-guided core biopsies of the breast: reducing the burden of repeat biopsies in patients presenting to the breast clinic"]. Breast. 19 (2): 105–8. doi:10.1016/j.breast.2009.12.003. PMID 20074953.