Hepatocellular adenoma CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Overview

The CT scan appearances of hepatocellular adenoma are usually variable and characteristic lesions are best seen with multiphase helical CT scanning. The CT scan findings include; nonlobulated well marginated mass that can be encapsulated and is rarely calcified, heterogeneous hypoattenuating area within the tumor seen in necrosis or old hemorrhage, and larger hepatocellular adenomas may be more heterogeneous than smaller lesions and their CT scan appearance is less specific.

CT

  • The CT scan appearances of hepatocellular adenoma are usually variable, and classical characteristic lesions of adenoma are best seen with multi-phase helical CT scan.[1]
  • The CT scan findings of hepatocellular carcinoma include;[2][3][4][5][6]
    • Non lobulated, well marginated mass that can be encapsulated and is rarely calcified.
    • Homogeneous enhancement in the arterial phase. It is usually isoattenuating but sometimes mildly hypoattenuating relative to normal liver on un enhanced portal venous phase and delayed phase images.
    • The presence of intratumoral fat can show a hypoattenuating mass, if it is surrounded by a fatty liver it appears hyperattenuating on all contrast phases and unenhanced images.
    • A heterogenous, hypoattenuating area within the tumor is seen in necrosis or old hemorrhage.
    • The larger hepatocellular adenomas may be more heterogeneous than smaller lesions and their CT scan appearance is less specific.

References

  1. . doi:10.1594/ecr2013/C-2620. Missing or empty |title= (help)
  2. Bipin Valchandji Daga, Vaibhav R. Shah & Rahul B. More (2012). "CT scan diagnosis of hepatic adenoma in a case of von Gierke disease". The Indian journal of radiology & imaging. 22 (1): 54–57. doi:10.4103/0971-3026.95405. PMID 22623817. Unknown parameter |month= ignored (help)
  3. Ludger Barthelmes & Iain S. Tait (2005). "Liver cell adenoma and liver cell adenomatosis". HPB : the official journal of the International Hepato Pancreato Biliary Association. 7 (3): 186–196. doi:10.1080/13651820510028954. PMID 18333188.
  4. T. J. Welch, P. F. 2nd Sheedy, C. M. Johnson, D. H. Stephens, J. W. Charboneau, M. L. Brown, G. R. May, M. A. Adson & D. B. McGill (1985). "Focal nodular hyperplasia and hepatic adenoma: comparison of angiography, CT, US, and scintigraphy". Radiology. 156 (3): 593–595. doi:10.1148/radiology.156.3.3895291. PMID 3895291. Unknown parameter |month= ignored (help)
  5. H. Dharmana, S. Saravana-Bawan, S. Girgis & G. Low (2017). "Hepatocellular adenoma: imaging review of the various molecular subtypes". Clinical radiology. 72 (4): 276–285. doi:10.1016/j.crad.2016.12.020. PMID 28126185. Unknown parameter |month= ignored (help)
  6. Dhingra, Sadhna; Fiel, M. Isabel (2014). "Update on the New Classification of Hepatic Adenomas: Clinical, Molecular, and Pathologic Characteristics". Archives of Pathology & Laboratory Medicine. 138 (8): 1090–1097. doi:10.5858/arpa.2013-0183-RA. ISSN 0003-9985.


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