Astrocytoma medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.

Overview

The optimal therapy for astrocytoma depends on the stage at diagnosis. Chemotherapy is recommended for children. Radiation and chemotherapy with stem cell transplant is recommended for adults with high grade astrocytoma.

Medical Therapy

• Post surgical medical therapy is recommended in all patients with astrocytoma tumor.

Astrocytoma

• 1 Grade 1 and 2 - Low grade astrocytomas
  • 1.1 Wait and see
  • 1.2 Radiation therapy
  • 1.3 Adjunctive chemotherapy

• 2 Grade 3 - Anaplastic astrocytoma
  • 2.1 Radiotherpay+ chemotherapy
    • Procarbazine, lomustine, vincristine
    • Procarbazine, lomustine, temozolomide

• 3 Grade 4 - Glioblastoma multiform
  • 3.1 Chemotherapy
    • 3.1.1 Temozolomide
  • 3.2 Bevacizumab
  • 3.3 Alternating electric fields
  • 3.4 Carmustine polymer wafers