Pleomorphic adenoma classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Pleomorphic adenoma can be classified into 4 subgroups on the basis of histological appearance and stromal content. Subgroup 1(30-50%) of stromal content, subgroup 2(80%), subgroup 3(20-30%), subgroup 4(6%).

Classification

• Pleomorphic adenoma can be classified on the basis of the histological picture i.e, epithelial and stromal changes into the following subgroups.
  • Subgroup 1 (30,5%) is the classical pleomorphic adenoma with a stroma content of 30-50%
  • subgroup 2 (55%) has a stroma content of 80%
  • subgroup 3 (9%) has a poor stroma content of 20-30% or less and an epithelial differentiation similar to subgroup 1
  • subgroup 4 has also a poor stroma content (6%) with a relatively monomorphic epithelial structure.