Pleomorphic adenoma other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
The other diagnostic studies available for pleomorphic adenoma are FNA and core biopsy.
Other Diagnostic Studies
- Pleomorphic adenoma may also be diagnosed using fine needle aspiration (FNA) and core needle biopsy.
- FNA can determine whether the tumor is malignant in nature with a sensitivity approximately 90%<ref name="CohenPatel2004">Cohen, Erik G.; Patel, Snehal G.; Lin, Oscar; Boyle, Jay O.; Kraus, Dennis H.; Singh, Bhuvanesh; Wong, Richard J.; Shah, Jatin P.; Shaha, Ashok R. (2004). "Fine-Needle Aspiration Biopsy of Salivary Gland Lesions in a Selected Patient Population". Archives of Otolaryngology–Head & Neck Surgery. 130 (6): 773. doi:10.1001/archotol.130.6.773. ISSN 0886-4470.
- FNA can also distinguish primary salivary tumor from metastatic disease.
- Core needle biopsy is more accurate compared to FNA with diagnostic accuracy greater than 97%
- Findings on fine needle aspiration (FNA) and core needle biopsy, include:
- Admixture of polygonal epithelial and spindle-shaped myoepithelial elements
- Mesenchymal stroma (important feature)
- Proliferation of myoepithelium and epithelium