Acute lymphoblastic leukemia diagnostic study of choice
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Shyam Patel [2]
Overview
The diagnostic study of choice for acute lymphoblastic lymphoma is bone marrow biopsy.
Diagnostic study of choice
- The diagnostic study of choice for acute lymphoblastic lymphoma is bone marrow biopsy.
- A bone marrow biopsy must show 20% or greater blasts of lymphoid immunophenotype[1]
- This diagnostic criteria is very similar to that of acute myeloid leukemia.[2]
Diagnostic results
On bone marrow biopsy the following result is a confirmation of acute lymphoblastic leukemia:
Sequence of Diagnostic Studies
The various investigations must be performed in the following order:
References
- ↑ Chiaretti S, Zini G, Bassan R (2014). "Diagnosis and subclassification of acute lymphoblastic leukemia". Mediterr J Hematol Infect Dis. 6 (1): e2014073. doi:10.4084/MJHID.2014.073. PMC 4235437. PMID 25408859.
- ↑ Terwilliger T, Abdul-Hay M (2017). "Acute lymphoblastic leukemia: a comprehensive review and 2017 update". Blood Cancer J. 7 (6): e577. doi:10.1038/bcj.2017.53. PMC 5520400. PMID 28665419.