Cowden syndrome screening
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Cowden syndrome screening On the Web |
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Risk calculators and risk factors for Cowden syndrome screening |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
According to the National Comprehensive Cancer Network (NCCN) Guidelines, screening for cowden syndrome patients is recommended for women who are at risk for breast cancer, uterine cancer and colon cancer.
Screening
According to the National Comprehensive Cancer Network (NCCN) Guidelines, screening for cowden syndrome patients is recommended for women who are at risk for:
- Breast cancer
- Starting at the age of 25 years, breast exam should be considered for every 6-12 months.[1]
- Starting at the age of 30-35 years, patients should consider magnetic resonance imaging (MRI) and and mammogram.
- Patients who are at risk for breast cancer also should consider 3D mammography.
- Uterine cancer
- Colon cancer
- Starting at the age of 35 years, for every 5 years colonoscopy should be considered.
- Thyroid cancer
- Patients at all ages should consider an annual thyroid examination with an ultrasound scan is recommended.
References
- ↑ FitzGerald MG, Marsh DJ, Wahrer D, Bell D, Caron S, Shannon KE, Ishioka C, Isselbacher KJ, Garber JE, Eng C, Haber DA (August 1998). "Germline mutations in PTEN are an infrequent cause of genetic predisposition to breast cancer". Oncogene. 17 (6): 727–31. doi:10.1038/sj.onc.1201984. PMID 9715274.