Ovarian germ cell tumor medical therapy

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Ovarian germ cell tumor Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2] Monalisa Dmello, M.B,B.S., M.D. [3]

Overview

Medical Therapy

Treatment during pregnancy

Chemotherapy for malignant ovarian germ cell tumors and ovarian function

The long term effects of chemotherapy on ability of ovary for future pregnancies has been studied and the results are as following:

References

  1. "NCCN Clinical Practice Guidelines in Oncology: Ovarian Cancer. National comprehensive cancer network, 2011; http://www.nccn.org/professionals/physician_gls/pdf/ovarian.pdf."
  2. Gershenson, D M; Morris, M; Cangir, A; Kavanagh, J J; Stringer, C A; Edwards, C L; Silva, E G; Wharton, J T (1990). "Treatment of malignant germ cell tumors of the ovary with bleomycin, etoposide, and cisplatin". Journal of Clinical Oncology. 8 (4): 715–720. doi:10.1200/JCO.1990.8.4.715. ISSN 0732-183X.
  3. Segelov, E; Campbell, J; Ng, M; Tattersall, M; Rome, R; Free, K; Hacker, N; Friedlander, M L (1994). "Cisplatin-based chemotherapy for ovarian germ cell malignancies: the Australian experience". Journal of Clinical Oncology. 12 (2): 378–384. doi:10.1200/JCO.1994.12.2.378. ISSN 0732-183X.
  4. Dimopoulos, Meletios A.; Papadimitriou, Christos; Hamilos, Georgios; Efstathiou, Eleni; Vlahos, Georgios; Rodolakis, Alexandros; Aravantinos, Gerassimos; Kalofonos, Haralambos; Kouroussis, Charalambos; Gika, Dimitra; Skarlos, Dimosthenis; Bamias, Aristotle (2004). "Treatment of ovarian germ cell tumors with a 3-day bleomycin, etoposide, and cisplatin regimen: a prospective multicenter study". Gynecologic Oncology. 95 (3): 695–700. doi:10.1016/j.ygyno.2004.08.018. ISSN 0090-8258.
  5. Hubalek, Michael; Smekal-Schindelwig, Caecilia; Zeimet, Alain G.; Sergi, Consolato; Brezinka, Christoph; Mueller-Holzner, Elisabeth; Marth, Christian (2007). "Chemotherapeutic treatment of a pregnant patient with ovarian dysgerminoma". Archives of Gynecology and Obstetrics. 276 (2): 179–183. doi:10.1007/s00404-007-0328-2. ISSN 0932-0067.
  6. 6.0 6.1 Amant, Frédéric; Halaska, Michael J.; Fumagalli, Monica; Dahl Steffensen, Karina; Lok, Christianne; Van Calsteren, Kristel; Han, Sileny N.; Mir, Olivier; Fruscio, Robert; Uzan, Cathérine; Maxwell, Cynthia; Dekrem, Jana; Strauven, Goedele; Mhallem Gziri, Mina; Kesic, Vesna; Berveiller, Paul; van den Heuvel, Frank; Ottevanger, Petronella B.; Vergote, Ignace; Lishner, Michael; Morice, Philippe; Nulman, Irena (2014). "Gynecologic Cancers in Pregnancy: Guidelines of a Second International Consensus Meeting". International Journal of Gynecologic Cancer. 24 (3): 394–403. doi:10.1097/IGC.0000000000000062. ISSN 1048-891X.
  7. Cardonick, Elyce; Iacobucci, Audrey (2004). "Use of chemotherapy during human pregnancy". The Lancet Oncology. 5 (5): 283–291. doi:10.1016/S1470-2045(04)01466-4. ISSN 1470-2045.
  8. Khi C, Low JJ, Tay EH, Chew SH, Ho TH (2002). "Malignant ovarian germ cell tumors: the KK Hospital experience". Eur. J. Gynaecol. Oncol. 23 (3): 251–6. PMID 12094965.
  9. Zanetta, Gerardo; Bonazzi, Cristina; Cantù, Maria Grazia; Bini†, Sergio; Locatelli, Anna; Bratina, Giorgio; Mangioni, Costantino (2001). "Survival and Reproductive Function After Treatment of Malignant Germ Cell Ovarian Tumors". Journal of Clinical Oncology. 19 (4): 1015–1020. doi:10.1200/JCO.2001.19.4.1015. ISSN 0732-183X.
  10. 10.0 10.1 Gershenson, D M (1988). "Menstrual and reproductive function after treatment with combination chemotherapy for malignant ovarian germ cell tumors". Journal of Clinical Oncology. 6 (2): 270–275. doi:10.1200/JCO.1988.6.2.270. ISSN 0732-183X.
  11. Weinberg, Lori E.; Lurain, John R.; Singh, Diljeet K.; Schink, Julian C. (2011). "Survival and reproductive outcomes in women treated for malignant ovarian germ cell tumors". Gynecologic Oncology. 121 (2): 285–289. doi:10.1016/j.ygyno.2011.01.003. ISSN 0090-8258.
  12. Low JJ, Perrin LC, Crandon AJ, Hacker NF (July 2000). "Conservative surgery to preserve ovarian function in patients with malignant ovarian germ cell tumors. A review of 74 cases". Cancer. 89 (2): 391–8. PMID 10918171.

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