Acute lymphoblastic leukemia x ray

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2] Carlos A Lopez, M.D. [3]

Overview

Bone X-ray in acute lymphoblastic leukemia is characterized by periosteal reaction.

An X-ray may be helpful in the diagnosis of acute lymphoblastic leukemia
Findings on an x-ray suggestive of acute lymphoblastic leukemia include periosteal reaction^[1]
This radiographic feature is similar to that of osteosarcoma.
The following is also seen on bone x-rays in acute lymphoblastic leukemia:^[2]
- Radiolucent metaphyseal bands^[3]
- Coarse trabeculation^[4]
- Periosteal reactions^[5]
- Osteopenia^[6]

↑ Shahnazi M, Khatami A, Shamsian B, Haerizadeh B, Mehrafarin M (2012). "Bony lesions in pediatric acute leukemia: pictorial essay". Iran J Radiol. 9 (1): 50–6. doi:10.5812/iranjradiol.6765. PMC 3522339. PMID 23329962.
↑ Tafaghodi F, Aghighi Y, Rokni Yazdi H, Shakiba M, Adibi A (2009). "Predictive plain X-ray findings in distinguishing early stage acute lymphoblastic leukemia from juvenile idiopathic arthritis". Clin Rheumatol. 28 (11): 1253–8. doi:10.1007/s10067-009-1221-0. PMID 19621208.
↑ Riccio I, Marcarelli M, Del Regno N, Fusco C, Di Martino M, Savarese R; et al. (2013). "Musculoskeletal problems in pediatric acute leukemia". J Pediatr Orthop B. 22 (3): 264–9. doi:10.1097/BPB.0b013e32835d731c. PMID 23407432.
↑ Navarro, Shannon M.; Matcuk, George R.; Patel, Dakshesh B.; Skalski, Matthew; White, Eric A.; Tomasian, Anderanik; Schein, Aaron J. (2017). "Musculoskeletal Imaging Findings of Hematologic Malignancies". RadioGraphics. 37 (3): 881–900. doi:10.1148/rg.2017160133. ISSN 0271-5333.
↑ Angsubhakorn, Natthapon; Suvannasankha, Attaya (2018). "Acute lymphoblastic leukaemia with osteolytic bone lesions: diagnostic dilemma". BMJ Case Reports: bcr-2018–225008. doi:10.1136/bcr-2018-225008. ISSN 1757-790X.
↑ Mostoufi-Moab S, Halton J (2014). "Bone morbidity in childhood leukemia: epidemiology, mechanisms, diagnosis, and treatment". Curr Osteoporos Rep. 12 (3): 300–12. doi:10.1007/s11914-014-0222-3. PMC 4131149. PMID 24986711.