Seminoma epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Testicular germ cell tumor accounts for around 1-2% of all malignancies in males up to the age of 65, but they are the most common nonhematologic malignancy in males 15-49 years old. Approximately 50% of germ cell tumours are seminomas. The mean age at diagnosis of testicular seminoma is between 15 and 35 years. This is about 5 to 10 years older than men with other germ cell tumors of the testis. Testicular seminoma usually affects individuals of the Caucasian race. African american individuals are less likely to develop testicular seminoma.
Epidemiology
Prevalence
Testicular germ cell tumor accounts for around 1-2% of all malignancies in males up to the age of 65, but they are the most common nonhematologic malignancy in males 15-49 years old. Approximately 50% of germ cell tumours are seminomas.[1]
Incidence
- The prevalence of seminoma is approximately per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
- In 2009, the American Cancer Society estimated that there were 8,400 new cases and 380 related deaths from testicular cancer.[
Prevalence
- Testicular cancer is the most common type of cancer in young males.[2][3]
- Germ cell tumors are about 98% of testicular cancer.[4]
- About 55% of germ cell tumors are seminomas
- About 44% of germ cell tumors are non-seminomas
- About 1-2% of germ cell tumors are spermatocytic
- In the United States, the estimate prevalence of testicular cancer is approximately 9,310 new cases in 2018.[5]
- The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
- The prevalence of [disease/malignancy] is estimated to be [number] cases annually.
Case-fatality rate/Mortality rate
- In 2009, the incidence of testicular germ cell tumor is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
- The case-fatality rate/mortality rate of [disease name] is approximately [number range].
Age
- Seminoma commonly affects individuals young adults 15 and 35 years of age.[6]
- Seminoma is usually first diagnosed among 34 years (median, 39.5 years).[7]
Race
- Seminoma usually affects individuals of the white race. Black individuals are less likely to develop seminoma (ratio of 5 : 1).[8]
Gender
- Seminoma affects exclusively in men.
Region
- The majority of seminoma cases are reported in Europe, Scandinavia and North America.[9]
References
- ↑ Epidemiology of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016
- ↑ Shanmugalingam T, Soultati A, Chowdhury S, Rudman S, Van Hemelrijck M (October 2013). "Global incidence and outcome of testicular cancer". Clin Epidemiol. 5: 417–27. doi:10.2147/CLEP.S34430. PMC 3804606. PMID 24204171.
- ↑ Siegel RL, Miller KD, Jemal A (January 2019). "Cancer statistics, 2019". CA Cancer J Clin. 69 (1): 7–34. doi:10.3322/caac.21551. PMID 30620402.
- ↑ Chia VM, Quraishi SM, Devesa SS, Purdue MP, Cook MB, McGlynn KA (May 2010). "International trends in the incidence of testicular cancer, 1973-2002". Cancer Epidemiol. Biomarkers Prev. 19 (5): 1151–9. doi:10.1158/1055-9965.EPI-10-0031. PMC 2867073. PMID 20447912.
- ↑ "Testicular Cancer - Cancer Stat Facts".
- ↑ Che, Mingxin; Tamboli, Pheroze; Ro, Jae Y.; Park, Dong Soo; Ro, Jung Sil; Amato, Robert J.; Ayala, Alberto G. (2002). "Bilateral testicular germ cell tumors". Cancer. 95 (6): 1228–1233. doi:10.1002/cncr.10804. ISSN 0008-543X.
- ↑ Di Gregorio M, Nollevaux MC, Lorge F, D'Hondt L (May 2016). "Metachronous testicular seminoma after radiotherapy and chemotherapy: a case report". World J Surg Oncol. 14: 147. doi:10.1186/s12957-016-0902-9. PMC 4867539. PMID 27184033.
- ↑ McGlynn KA, Cook MB (November 2009). "Etiologic factors in testicular germ-cell tumors". Future Oncol. 5 (9): 1389–402. doi:10.2217/fon.09.116. PMC 3000220. PMID 19903067.
- ↑ Shanmugalingam T, Soultati A, Chowdhury S, Rudman S, Van Hemelrijck M (October 2013). "Global incidence and outcome of testicular cancer". Clin Epidemiol. 5: 417–27. doi:10.2147/CLEP.S34430. PMC 3804606. PMID 24204171.