Seminoma history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]

Overview

Most common presentation of testicular seminoma is a painless testicular mass, although 45% will report a degree of testicular discomfort.^[1]
Bilateral tumors are rare (~2%) and are almost always asynchronous.
Diagnosis following trauma is common as it draws the patient’s attention to the lump.
Back pain, abdominal discomfort, or abdominal mass may be a presenting feature in the 25% of patients who have retroperitoneal nodal metastases.
Presentation with distant or extranodal metastases is rare (5%).
- The majority of patients with [disease name] are asymptomatic. OR
- The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
- Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].

Patients with [disease name]] may have a positive history of:

↑ Clinical presentation of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016
↑ ^2.0 ^2.1 Bosl GJ, Motzer RJ (July 1997). "Testicular germ-cell cancer". N. Engl. J. Med. 337 (4): 242–53. doi:10.1056/NEJM199707243370406. PMID 9227931.
↑ Motzer, Robert J.; Agarwal, Neeraj; Beard, Clair; Bhayani, Sam; Bolger, Graeme B.; Buyyounouski, Mark K.; Carducci, Michael A.; Chang, Sam S.; Choueiri, Toni K.; Gupta, Shilpa; Hancock, Steven L.; Hudes, Gary R.; Jonasch, Eric; Kuzel, Timothy M.; Lau, Clayton; Levine, Ellis G.; Lin, Daniel W.; Margolin, Kim A.; Michaelson, M. Dror; Olencki, Thomas; Pili, Roberto; Ratliff, Thomas W.; Redman, Bruce G.; Robertson, Cary N.; Ryan, Charles J.; Sheinfeld, Joel; Wang, Jue; Wilder, Richard B. (2012). "Testicular Cancer". Journal of the National Comprehensive Cancer Network. 10 (4): 502–535. doi:10.6004/jnccn.2012.0050. ISSN 1540-1405.