Retinoblastoma MRI
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [3]
Overview
On head and neck MRI, retinoblastoma is characterized by isointense to hyperintense mass on T1-weighted MRI and hypointense mass on T2-weighted MRI.
MRI
- MRI imaging study of retinoblastoma first introduced in 1980.[1]
- This method is used as an extra diagnostic method to CT scan in suspected retinoblastoma cases especially in those whose CT scan imaging is doubtful for the presence of extra-ocular extension.[2]
- MRI diagnostic value in the diagnosis of advanced retinoblastoma is greater than CT scan.[3]
MRI findings diagnostic of retinoblastoma are:
- On T1 image:Hyperintense mass compared to vitrous body
- On T2 image:Hypointense mass compared to vitrous body
- It should be mentined that MRI is accurate for tumor staging and evaluation of metastatic risk factors.[4]
- This imaging study is capable to discreminate the tumor with secondary retinal detachment from other causes of subretinal effusion or detachment, such as coat's disease, primary hyperplastic vitreous and retinopathy of prematurity.
- Also, some expert argue that CT imaging studies in bilateral retinoblastoma individuals will increase the risk of individuals for future malignancies. MRI is not associated with such risk.
References
- ↑ Schueler, A O (2003). "High resolution magnetic resonance imaging of retinoblastoma". British Journal of Ophthalmology. 87 (3): 330–335. doi:10.1136/bjo.87.3.330. ISSN 0007-1161.
- ↑ Meel R, Radhakrishnan V, Bakhshi S (April 2012). "Current therapy and recent advances in the management of retinoblastoma". Indian J Med Paediatr Oncol. 33 (2): 80–8. doi:10.4103/0971-5851.99731. PMC 3439795. PMID 22988349.
- ↑ de Jong, Marcus C.; de Graaf, Pim; Noij, Daniel P.; Göricke, Sophia; Maeder, Philippe; Galluzzi, Paolo; Brisse, Hervé J.; Moll, Annette C.; Castelijns, Jonas A. (2014). "Diagnostic Performance of Magnetic Resonance Imaging and Computed Tomography for Advanced Retinoblastoma". Ophthalmology. 121 (5): 1109–1118. doi:10.1016/j.ophtha.2013.11.021. ISSN 0161-6420.
- ↑ de Graaf, Pim; Barkhof, Frederik; Moll, Annette C.; Imhof, Saskia M.; Knol, Dirk L.; van der Valk, Paul; Castelijns, Jonas A. (2005). "Retinoblastoma: MR Imaging Parameters in Detection of Tumor Extent". Radiology. 235 (1): 197–207. doi:10.1148/radiol.2351031301. ISSN 0033-8419.
- ↑ 5.0 5.1 5.2 Image courtesy of Radswiki Radiopaedia (original file [1]).[http://radiopaedia.org/licence Creative Commons BY-SA-NC