Progeria epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Epidemiology and Demographics

Incidence

• The incidence of Hutchinson-Gilford progeria syndrome (HGPS) is approximately one in four to eight million births worldwide.
• The incidence of Hutchinson-Gilford progeria syndrome (HGPS) in Netherlands is 1:4,000,000.

Prevalence

• The prevalence of Hutchinson-Gilford progeria syndrome (HGPS) is approximately 1 in 20 million individuals worldwide.

Case-fatality rate/Mortality rate

• In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
• The case-fatality rate/mortality rate of [disease name] is approximately [number range].

Age

• Patients of all age groups may develop [disease name].
• The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
• [Disease name] commonly affects individuals younger than/older than [number of years] years of age.
• [Chronic disease name] is usually first diagnosed among [age group].
• [Acute disease name] commonly affects [age group].

Race

• [Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].

Gender

• Hutchinson-Gilford progeria syndrome (HGPS) affects men and women equally but males are little more commonly affected by Hutchinson-Gilford progeria syndrome (HGPS) than females. The male to female ratio is approximately 1.2:1.

Region

• The majority of [disease name] cases are reported in [geographical region].

• [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].