Lipoid pneumonia epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2]

Overview

The incidence and prevalence of lipoid pneumonia are underestimated. It is mostly because of similarities between pneumonias from different causes and lack of specific marker to distinguish pneumonias from each other. In 2019 there was an outbreak of vaping based pulmonary complications.

Epidemiology and Demographics

Incidence

  • In 2019 there was an outbreak of vaping based pulmonary complications.
  • The majority of underlying cause of morbidity was lipoid pneumonia.
  • The incidence of cases differentiated based on state can be seen on :"Outbreak of Lung Injury Associated with E-Cigarette Use, or Vaping".
  • The incidence and prevalence of lipoid pneumonia are underestimated. It is mostly because of similarities between pneumonias from different causes and lack of specific marker to distinguish pneumonia from each other.[1]
  • There is no prediction of incidence of lipoid pneumonia but the incidence of lipoid pneumonia is approximately 300,000 to 600,000 individuals annually in the United States.[2]

Prevalence

  • There is no study about prevalence of lipoid pneumonia.

Mortality rate

  • Prognosis of lipoid pneumonia is usually indolent, however, it may also be progressive.[3]
  • Lipoid pneumonia is not usually a cause of death. Most patients suffer from complications such as superinfection, cor pulmonale or lung cancer which may be mortal.[4][5][6][7]

Age

  • Lipoid pneumonia commonly affects children and elderly.[8]
  • The incidence of lipoid pneumonia increases with age; the median age at diagnosis is 70-80 years.[9]

Gender

  • There is no gender preference in lipoid pneumonia.[10]

References

  1. Lanspa, Michael J.; Jones, Barbara E.; Brown, Samuel M.; Dean, Nathan C. (2013). "Mortality, morbidity, and disease severity of patients with aspiration pneumonia". Journal of Hospital Medicine. 8 (2): 83–90. doi:10.1002/jhm.1996. ISSN 1553-5592.
  2. Marik, Paul E. (2001). "Aspiration Pneumonitis and Aspiration Pneumonia". New England Journal of Medicine. 344 (9): 665–671. doi:10.1056/NEJM200103013440908. ISSN 0028-4793.
  3. Gondouin, A.; Manzoni, Ph.; Ranfaing, E.; Brun, J.; Cadranel, J.; Sadoun, D.; Cordier, J.F.; Depierre, A.; Dalphin, J.C. (1996). "Exogenous lipid pneumonia: a retrospective multicentre study of 44 cases in France". European Respiratory Journal. 9 (7): 1463–1469. doi:10.1183/09031936.96.09071463. ISSN 0000-0000.
  4. Greenberger PA, Katzenstein AL (1983). "Lipid pneumonia with atypical mycobacterial colonization. Association with allergic bronchopulmonary aspergillosis". Arch Intern Med. 143 (10): 2003–5. PMID 6625788.
  5. Dixon C, Bolivar R, Katz R, McMurtrey M (1985). "Lipoid pneumonia and Mycobacterium fortuitum pulmonary infection: successful treatment with sulfisoxazole". Tex Med. 81 (3): 57–60. PMID 3983869.
  6. Greenaway, T. M.; Caterson, I. D. (1989). "HYPERCALCEMIA AND LIPOID PNEUMONIA". Australian and New Zealand Journal of Medicine. 19 (6): 713–715. doi:10.1111/j.1445-5994.1989.tb00342.x. ISSN 0004-8291.
  7. Casey, James F. (1961). "Chronic Cor Pulmonale Associated with Lipoid Pneumonia". JAMA. 177 (13): 896. doi:10.1001/jama.1961.03040390010003. ISSN 0098-7484.
  8. Lanspa, Michael J.; Peyrani, Paula; Wiemken, Timothy; Wilson, Emily L.; Ramirez, Julio A.; Dean, Nathan C. (2015). "Characteristics associated with clinician diagnosis of aspiration pneumonia: A descriptive study of afflicted patients and their outcomes". Journal of Hospital Medicine. 10 (2): 90–96. doi:10.1002/jhm.2280. ISSN 1553-5592.
  9. Lanspa, Michael J.; Jones, Barbara E.; Brown, Samuel M.; Dean, Nathan C. (2013). "Mortality, morbidity, and disease severity of patients with aspiration pneumonia". Journal of Hospital Medicine. 8 (2): 83–90. doi:10.1002/jhm.1996. ISSN 1553-5592.
  10. Kim, Chang Ho; Kim, Eun Jin; Lim, Jae Kwang; Yoo, Seung Soo; Lee, Shin Yup; Cha, Seung Ick; Park, Jae Yong; Lee, Jaehee (2018). "Comparison of exogenous and endogenous lipoid pneumonia: the relevance to bronchial anthracofibrosis". Journal of Thoracic Disease. 10 (4): 2461–2466. doi:10.21037/jtd.2018.04.06. ISSN 2072-1439.