Constrictive pericarditis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Pericardial constriction has been associated with, protein losing enteropathy, nephrotic syndrome, and LFT abnormalities consistent with hepatic congestion and chylous ascites.

Laboratory findings

• Complete blood count (CBC)
  • Dilutional anemia if congestive heart failure (CHF) is present
• Leukocytosis
  • Infectious, bacteriologic, or rheumatologic etiology source or steroid therapy
• Leukopenia
  • Malignancy and chemotherapeutic agents use
• hyponatremia or pseudohyponatremia
• Contraction alkalosis (hypochloremia with hypercarbia)
• elevation of blood urea nitrogen (BUN) levels f
• serum creatinine levels are observed
• arterial blood gas measurement,
• metabolic acidosis (ie, low pH and low bicarbonate),
• with or without compensatory respiratory alkalosis (ie, decreased partial pressure of carbon dioxide
• elevated transaminase levels
• Hypoalbuminemia ( a protein-losing enteropathy (PLE)
• proteinuria (nephrotic range)
• elevated sedimentation rate (ESR), C-reactive protein (CRP) level (postpericardiotomy syndrome)
• normocytic normochromic anemia
• brain natriuretic peptide (BNP), mildly increased (<150 ng/L).
• associated collagen vascular disorder (antinuclear antibody (ANA) or rheumatoid factor (RF))
• purified protein derivative (PPD) skin test (TB)