Eisenmenger’s syndrome epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Abdelrahman Ibrahim Abushouk, MD[2]
Overview
Epidemiology and Demographics
Incidence
- The incidence of ES decreased from 2.5/million inhabitants/year in 1977 to 0.2/million inhabitants/year in 2012.
Prevalence
- Overall, about 8% of patients with congenital heart disease develop Eisenmenger's syndrome.[1]
- About 3% of patients with a small VSD (≤1.5 cm) and 50% of patients with a large VSD (>1.5 cm) develop Eisenmenger's syndrome.[2]
- However, the prevalence is currently decreasing due to improved detection methods of congenital heart defects.
- The prevalence decreased from 24.6 to 11.9/million inhabitants.
Case-fatality rate/Mortality rate
- The case-fatality rate/mortality rate of [disease name] is approximately [number range].
Age
- Eisenmenger's syndrome usually manifests before puberty.
- But it may also manifest during adolescence and early adulthood.[3]
Race
- There is no racial predilection to Eisenmenger's syndrome.
Gender
- Eisenmenger's syndrome affects men and women equally.
Developed Countries
The prevalence of Eisenmenger's syndrome is less common in developed countries due to better healthcare access.
Developing Countries
The prevalence of Eisenmenger's syndrome is more common in developing countries due to poor healthcare access.
References
- ↑ Daliento L, Somerville J, Presbitero P, Menti L, Brach-Prever S, Rizzoli G; et al. (1998). "Eisenmenger syndrome. Factors relating to deterioration and death". Eur Heart J. 19 (12): 1845–55. doi:10.1053/euhj.1998.1046. PMID 9886728.
- ↑ Kidd L, Driscoll DJ, Gersony WM, Hayes CJ, Keane JF, O'Fallon WM; et al. (1993). "Second natural history study of congenital heart defects. Results of treatment of patients with ventricular septal defects". Circulation. 87 (2 Suppl): I38–51. PMID 8425321.
- ↑ Daliento L, Somerville J, Presbitero P, Menti L, Brach-Prever S, Rizzoli G; et al. (1998). "Eisenmenger syndrome. Factors relating to deterioration and death". Eur Heart J. 19 (12): 1845–55. doi:10.1053/euhj.1998.1046. PMID 9886728.