Andersen-Tawil syndrome epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Andersen-Tawil syndrome is a rare hereditary multisystem disorder transmitted in autosomal dominant pattern. Only 200 cases of Andersen-Tawil syndrome were reported worldwide.

The incidence of Andersen-Tawil syndrome is approximately less than 1 per 100,000 individuals worldwide.^[1]
Only 200 cases of Andersen-Tawil syndrome were reported worldwide.
Patients who are suffering with periodic paralysis Andersen-Tawil syndrome only accounts for less than 10% of these patients.
In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.

The prevalence of Andersen-Tawil syndrome is unknown.
The prevalence of congenital Long QT syndrome(LQTS) is around 1 in 2000 births.^[2]
The prevalence of [disease/malignancy] is estimated to be [number] cases annually.

In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
The case-fatality rate/mortality rate of [disease name] is approximately [number range].

Patients of all age groups may develop [disease name].
The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
Andersen-Tawil syndrome commonly affects individuals of younger age, most commonly in the first decade of life younger than 10 years.
[Chronic disease name] is usually first diagnosed among [age group].
[Acute disease name] commonly affects [age group].

There is no racial predilection to Andersen-Tawil syndrome as of now.
[Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].

Andersen-Tawil syndrome affects men and women equally.
[Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.

↑ Nguyen, Hoai-Linh; Pieper, Gerard H.; Wilders, Ronald (2013). "Andersen–Tawil syndrome: Clinical and molecular aspects". International Journal of Cardiology. 170 (1): 1–16. doi:10.1016/j.ijcard.2013.10.010. ISSN 0167-5273.
↑ Schwartz PJ, Stramba-Badiale M, Crotti L, Pedrazzini M, Besana A, Bosi G; et al. (2009). "Prevalence of the congenital long-QT syndrome". Circulation. 120 (18): 1761–7. doi:10.1161/CIRCULATIONAHA.109.863209. PMC 2784143. PMID 19841298.