Right ventricular outflow tract obstruction pulmonary subvalvular stenosis

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Anatomy of Pulmonary Valve

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Pulmonary valve stenosis
Pulmonary subvalvular stenosis
Pulmonary supravalvular stenosis
Pulmonary atresia

Pathophysiology

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Differentiating Right ventricular outflow tract obstruction from other Diseases

Epidemiology and Demographics

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Associate Editor-in-Chief: Keri Shafer, M.D. [3]

Anatomy

  • There is hypertrophy of the infundibular muscle causing obstruction. [1] [2]
  • The isolated form is rare, more commonly develops in response to an underlying VSD. [2]

Clinical Features

  • Similar to valvar pulmonic stenosis. [1] [3]
  • Aortic stenosis was probably first described by Lazare Riviere (1589-1655), a French physician in 1663. [4] [5]
  • No poststenotic dilation of the pulmonary artery in contrast to valvar pulmonic stenosis. [2]
  • Aortic stenosis was probably first described by Lazare Riviere (1589-1655), a French physician in 1663. [4]. [6]

References

  1. 1.0 1.1 Pierpont ME, Basson CT, Benson DW, Gelb BD, Giglia TM, Goldmuntz E; et al. (2007). "Genetic basis for congenital heart defects: current knowledge: a scientific statement from the American Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young: endorsed by the American Academy of Pediatrics". Circulation. 115 (23): 3015–38. doi:10.1161/CIRCULATIONAHA.106.183056. PMID 17519398.
  2. 2.0 2.1 2.2 Schmoldt A, Benthe HF, Haberland G, Raffle A, Gray J, MacDonald HR, Ehrhart IC, Parker PE, Weidner WJ, Dabney JM, Scott JB, Haddy FJ, Gatzy JT (September 1975). "Digitoxin metabolism by rat liver microsomes". Biochem. Pharmacol. 24 (17): 1639–41. doi:10.1136/bmj.1.6001.93-a. PMC 5922622. PMID 10.
  3. Nazari S, Carli F, Salvi S, Banfi C, Aluffi A, Mourad Z; et al. (2000). "Patterns of systolic stress distribution on mitral valve anterior leaflet chordal apparatus. A structural mechanical theoretical analysis". J Cardiovasc Surg (Torino). 41 (2): 193–202. PMID 10901521.
  4. 4.0 4.1 {{cite journal| author=Vaslef SN, Roberts WC| title=Early descriptions of aortic valve stenosis. | journal=Am Heart J | year= 1993 | volume= 125 | issue= 5 Pt 1 | pages= 1465-74 | pmid=8480616 | doi=10.1016/0002-8703(93)91036-e | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?
  5. Neilson GH, Galea EG, Hossack KF (August 1978). "Thromboembolic complications of mitral valve disease". Aust N Z J Med. 8 (4): 372–6. doi:10.1111/j.1445-5994.1978.tb04904.x. PMID 282850.
  6. Baumgartner H, Hung J, Bermejo J, Chambers JB, Evangelista A, Griffin BP; et al. (2009). "Echocardiographic assessment of valve stenosis: EAE/ASE recommendations for clinical practice". J Am Soc Echocardiogr. 22 (1): 1–23, quiz 101-2. doi:10.1016/j.echo.2008.11.029. PMID 19130998.

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