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Rickets Microchapters |
Diagnosis |
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Treatment |
Case Studies |
MAH On the Web |
American Roentgen Ray Society Images of MAH |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Rickets Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
MAH On the Web |
American Roentgen Ray Society Images of MAH |
Overview
Rickets is a bony disease due to decreased mineralization of growth plate, associated with abnormal serum calcium and phosphate level[1]. This leads to softening of bones.Rickets is more common in children especially in developing countries due to malnutrition and famines. It can also occur in adults and similar presentation in adults is termed as osteomalacia. The origin of the word "rickets" is unknown. The Greek derived word "rachitis" (meaning "inflammation of the spine") was later adopted as the scientific term for rickets, due chiefly to the words' similarity in sound.
Historical Perspective
Classification
There are 3 types of rickets : 1. Nutritional Rickets (due to deficiency of Vit D, calcium, and phosphorous) 2. Vitamin D dependent rickets (due to defective metabolism of vitamin D) 3. Vitamin D resistant rickets (hypophosphatemic rickets due renal phosphate wasting)
Pathophysiology
Physiology
Pathogenesis
Genetics
Associated Conditions
Gross Pathology
Microscopic Pathology
References
- ↑ Shore RM, Chesney RW (2013). "Rickets: Part I." Pediatr Radiol. 43 (2): 140–51. doi:10.1007/s00247-012-2532-x. PMID 23208530.