| | | | | | UPOINT domains
Complications in Central Nervous System- Cerebrovascular Accident
- Hemorrhagic
- Ischaemic
- Acute Encephalitis
- Viral Meningitis
- Epileptic Seizures
- Encephalopathy
- Headache
Complications in Peripheral Nervous system- Guillain-Barre syndrome
- Anosmia
- Acute Myelitis
- Miller Fischer Sydrome
- Polyneuritis Cranialis
Ego defensesImmature Defenses- Acting Out
- Expressing unacceptable feelings and thoughts through actions
- Denial
- Avoiding the awreness of painful reality
- Displacemnet
- Transferring avoided ideas to neutral persons
- Idealization
- Expressing extreme positive thoughts of self and others while ignoring negative thoughts
- Identification
- Modeling behaviour after one person who is more powerful.
- These ego defenses are unconsious or conscious
DEFENSES
DEFENSES
Defenses
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Mature Defenses- Sublimitaion
- Replacing an unacceptable wish with a course of action that is similar to the wish but does not conflict with one's value system.
- Altruism
- alleviating negative feelings via unsolicited generosity.
- Suppression
- Intentionally withholding an idea or feeling.
16,Saturday,11,2024
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Phenotype Domains | Clinical presentation |
Urinary | Lower urinary tract symptoms that creates discomfort or High post-micturation residual volume |
Psychological | Patient with depression or severe anxiety thinking the worst will happen to them |
Organ-specific | Tend\erness in Prostate,Presence of blood in ejaculation,Leukocytes in prostatic fluid or post-massage urine |
Infectious | Infection with gram negative bacilli or Enterococii localized to prostate or presence of Ureaplasma in urine |
Systemic | Pain anywhere else in the body except abdomen or pelvis or having a diagnosis of fibromyalgia,chronic fatigue or irritable bowel syndrome |
Tenderness | Presence of palpable musvle spams in abodomen or pelvic floor |
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Increased behaviour
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Decreased behaviour
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Add stimulus
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(+)ve reinformation
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(+)ve punishment
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Remove stimulus
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(-)ve reinformation
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(-)ve punishment
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Tumor nomenclature
Carcinoma implies epithelial origin,whereas sarcoma denotes mesenchymal origin. Both terms imply malignancy.
terms for non-neoplastic malformations include hamartoma(disorganized overgrowth of tissues in their native location, eg, Peutz- Jeghes polyps) and choriostoma9 normal tissue in foreign location, eg, gastric tissue located in distal ileum in Meckel Diverticulum).
- Benign tumor may show well demarcation, well diffreentiation, low mitotic activity, no necrosis, no metastasis.
- Malignant tumor shows poor demarcation, poor mitotic activity, erratic growth, local invasion, metastasis, reduced apoptosis. Upregulation of telomerase prevents chromosome shortening and cell death.
CELL TYPE
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Benign
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Malignant
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Epithelium
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Adenoma,papilloma
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Adenocarcinoma, papillary carcinoma
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Messenchmye
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Blood cells
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lekaemia,Lymphoma
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Blood vessels
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Hemangioma
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Angiosarcoma
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Smooth muscle
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Leiomyoma
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Leiomyosarcoma
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Striated muscle
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Rhabdomyoma
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Rhabdomyosarcoma
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Connective tissue
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Fibroma
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Fibrosarcoma
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Bone
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Osteoma
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Osteosarcoma
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Fat
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Lipoma
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Liposarcoma
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Melanocyte
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Nevus/Mole
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Melanoma
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here is how we use reference
TYPE
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DEFINITION
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EXAMPLES
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STRATEGY TO REDUCE BIAS
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Selection Bias
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Error in assigning subjects to a study group resulting in an unreprestative sample.Most commomnly a sampling bias
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- Berkson Bias
- study population selected from hospital is less healthy than general population
- Healthy worker effect
- study population is healthier than the general population
- Non-response bias
- participating subjects differ from nonrespondents in meaningful ways.
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randomization
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Recall Bias
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Awareness of disorder alters recall by subjects; common in retrospective studies
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patients with disease recall exposure after learning of similar cases
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Decrease time from exposure to followup
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Measurement Bias
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Information is gathered in a systemically distorted manner.
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Association between HPV and cervical cancer not observed when using non-standarized classifications/
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Use objective, standardized, and previously tested methods of data collection that are planned ahead of time
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Procedure Bias
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subjects in different groups are not treated the same
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patients in treatment group spend more time in highly specialized hospital units
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Blinding and use of placebo
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Observer- expectancy Bias
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Researche's belief in the efficacy of a treatment changes the outcome of that treatment
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If observer expects treatment group to show signs of recovery, then he is more likely to document positive outcomes.
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Blinding
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Heart Failure
Clinical syndrome of cardiac pump dysfunction-->congestion and low perfusion.
Symptoms inlude dyspnea,orthopnea,fatigue; signs include rale,jugular venous distention(JVD),pitting edema.
- Systolic Dysfunction
- reduced EF,increased EDV;decreased contracility often secondary to ischaemia/MI or dialted cardiomyopathy
- Diastolic Dysfunction
- preserved EF, normal EDV;compliance often secondary to myocardial hypertrophy.
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Caused BY
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Skin
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Preload
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CO
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Afterload
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Treatment
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Hypovolumic
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hemorrhage,dehydration,burns
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Cold,clammy
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reduced
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reduced
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increased
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IV fluids
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Cardiogenic
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Acute MI,HF
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Cold,clammy
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increased
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reduced
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Increased
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Inotropes, diuresis
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Distributive
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Sepsis, anaphylaxis
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warm,dry
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reduced
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increased
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reduced
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IV fluids,pressors
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- this is how we add bullets
- this is how numbers are added
reference
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