Angiodysplasia natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nikita Singh, M.D.[2]

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Overview

Natural History

  • Small bowel angiodysplasia (SBA) contributes to 50% of obscure GI bleeding.
  • SBA tends to re-bleed more than angiodysplasia of the colon and stomach.
  • In a retrospective study, re-bleeding occurred after about 11 months of diagnosis in 80% of patients, and 3.5% died as a direct result of bleeding.
  • Multiple lesions and valvular heart diseases have been found to increase the risk of re-bleeding.
  • Apart from recurrence of bleeding, some other concerns in the natural history of angiodysplasia are transfusion requirements, hospital readmissions, and requirement endoscopic, pharmacological, or surgical therapy.
  • In asymptomatic people, the course of angiodysplasia is benign, and the bleeding risk is low. Consequently, treatment is not required for incidentally found lesions.

Complications

  • Anemia
  • Death from excessive blood loss
  • Side effects from treatment
  • Severe loss of blood from the GI tract

Prognosis

Patients who have bleeding related to this condition despite having had a colonoscopy, angiography, or surgery are likely to have more bleeding in the future. The outlook remains good if the bleeding is controlled.

References

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