Bornholm disease causes
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Arooj Naz
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Overview
Bornholm disease usually is caused by one of the group B coxsackie viruses and is less often caused by a group A coxsackie virus or an echovirus. The most prevalent Coxsackievirus virus strains included B3 and B4 followed by A4, A6, A9, and A10.
Causes
Bornholm disease is often due to either the Coxsackie virus or echovirus. The most prevalent strains include:
- Coxsackievirus B (CBV) types B3 and B4
- Coxsackievirus A (CAV) types 4, 6, 9 and 10
- Echovirus types 1, 6, 8, 9 and 19
Generally, Coxsackievirus B virus is more prevalent in regards to respiratory complaints compared to Coxsackievirus A strains. Apart from respiratory symptoms, the Coxsackievirus B virus has also presented with cases of aseptic meningitis, pericarditis, and orchitis. [1] The clinical spectrum varies depending on age groups for the Coxsackievirus A and B strains of the virus. Although severe progression of the disease is rare, it has been associated in particular with the Coxsackievirus B3 virus.[2]
References
- ↑ Lal A, Akhtar J, Isaac S, Mishra AK, Khan MS, Noreldin M | display-authors=etal (2018) Unusual cause of chest pain, Bornholm disease, a forgotten entity; case report and review of literature. Respir Med Case Rep 25 ():270-273. DOI:10.1016/j.rmcr.2018.10.005 PMID: 30364740
- ↑ Lee CJ, Huang YC, Yang S, Tsao KC, Chen CJ, Hsieh YC; et al. (2014). "Clinical features of coxsackievirus A4, B3 and B4 infections in children". PLoS One. 9 (2): e87391. doi:10.1371/journal.pone.0087391. PMC 3913601. PMID 24504149.