Fabry's disease epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Fabry's disease is a rare condition mainly underestimated due to its rarity and some nonspecific symptoms. This disease mostly affects men and has no rational disparities.
Epidemiology and Demographics
Prevalence
- In 2021, the prevalence of Fabry's disease was estimated to be approximately 1:17,000 to 1:117,000 in men.
- The prevalence of classic phenotype is estimated approximately 1:22,000 to 1:40,000 in men.
- The prevalence of atypical phenotype is about 1:1000 to 1:3000 in men and 1:6000 to 1:40,000 in females.[1]
Incidence
- Incidence of Fabry's disease is commonly underestimated.[1]
Gender
- Men are more commonly affected with Fabry's disease than females. The male to female ratio is approximately 2 to 1.[1]
Race
- The prevalence of Fabry's disease does not vary by race.[1]
References