ADAMTS5

ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2)
Identifiers
Symbol	ADAMTS5
Entrez	11096
HUGO	221
OMIM	605007
RefSeq	NM_007038
UniProt	Q9UNA0
Other data
Locus	Chr. 21 q22.1-q22

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Overview

ADAMTS5 (aggrecanase) is an enzyme that destroys cartilage in mice. Its discovery may lead to progress in human arthritis research. This enzyme may also be involved in cartilage deterioration in humans. It has been isolated and identified by Australian scientists in Sydney. ADAMTS5 has been indicated as being important in early osteoarthritis.

External links

• Rat Genome Database