Angiomyolipoma
Angiomyolipoma | |
ICD-10 | D30.0 |
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ICD-9 | 223.0 |
ICD-O: | M8860/0 |
DiseasesDB | 29496 |
MeSH | D018207 |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Angiomyolipoma is a benign renal lesion. It is a choristoma composed of variable amounts of fat, vascular, and smooth muscle elements. The lesion is well demarcated and contains mature elements. The incidence is about 0.3-3%. It occurs in more than 50% of individuals with tuberous sclerosis, often bilaterally.
It is twice as common in females as in males. The fat density of the tumour on CT is pathognomonic.
Types
- Isolated Angiomyolipoma (80%)
- Angiomyolipoma is about 4 times more common in women than in men.
- Interestingly, 80% of the cases involve the right kidney.
- Angiomyolipoma associated with tuberous sclerosis (20%).
- Angiomyolipoma occurs in 80% patients with tuberous sclerosis.
- Angiomyolipoma also occurs young women with lymphangiomyomatosis without other stigmata of tuberous sclerosis. AML and lymphangiomyomatosis are sometimes considered the forme fruste of tuberous sclerosis.
Diagnosis
- Most small lesions are asymptomatic and incidental findings on images.
- Complications include hematuria, flank pain, and shock as a result of spontaneous hemorrhage.
Diagnostic Findings
MRI, CT, and US images demonstrate an angiomyolipoma