Mutarotation

WikiDoc Resources for Mutarotation
Articles
Most recent articles on Mutarotation Most cited articles on Mutarotation Review articles on Mutarotation Articles on Mutarotation in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Mutarotation Images of Mutarotation Photos of Mutarotation Podcasts & MP3s on Mutarotation Videos on Mutarotation
Evidence Based Medicine
Cochrane Collaboration on Mutarotation Bandolier on Mutarotation TRIP on Mutarotation
Clinical Trials
Ongoing Trials on Mutarotation at Clinical Trials.gov Trial results on Mutarotation Clinical Trials on Mutarotation at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Mutarotation NICE Guidance on Mutarotation NHS PRODIGY Guidance FDA on Mutarotation CDC on Mutarotation
Books
Books on Mutarotation
News
Mutarotation in the news Be alerted to news on Mutarotation News trends on Mutarotation
Commentary
Blogs on Mutarotation
Definitions
Definitions of Mutarotation
Patient Resources / Community
Patient resources on Mutarotation Discussion groups on Mutarotation Patient Handouts on Mutarotation Directions to Hospitals Treating Mutarotation Risk calculators and risk factors for Mutarotation
Healthcare Provider Resources
Symptoms of Mutarotation Causes & Risk Factors for Mutarotation Diagnostic studies for Mutarotation Treatment of Mutarotation
Continuing Medical Education (CME)
CME Programs on Mutarotation
International
Mutarotation en Espanol Mutarotation en Francais
Business
Mutarotation in the Marketplace Patents on Mutarotation
Experimental / Informatics
List of terms related to Mutarotation

Overview

Mutarotation is the term given to the change in the specific rotation of plane polarized light, when it is passed through an aldohexose (a monosaccharides with six carbon atoms and H-C=O group). Mutarotation refers to the conversion of a pure anomer of a hemiacetal carbohydrate to an equilibrium mixture of two anomers.

As the name suggests, it is the change in rotation ("Muta" means "Change").

Plane polarized light is obtained by passing ordinary light through a nicol prism.

During mutarotation, either α or β forms keep changing into the chain structure periodically to and fro.

Mutarotation also refers to the interconversion between the α and β anomers. However it must be converted to the open chain structure first before it can change conformation to the α or β position.

For example, in glucose, carbon 1 (the aldehyde carbon) is the anomeric carbon. In fructose, carbon 2 (the keto carbon) is anomeric. Unlike the epimers, which are stable under ordinary conditions, anomers interconvert spontaneosly.