Multiple myeloma (patient information)
For the WikiDoc page for this topic, click here
Editor-in-Chief: Jinhui Wu, MD
Please Join in Editing This Page and Apply to be an Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
What is multiple myeloma?
Multiple myeloma is a cancer of plasma cells that is a type of white blood cell. The exact cause of multiple myeloma is not known. Epidemiological data suggest that it is more common in older people and African-Americans. Usual symptoms may include bone pain, broken bones, weakness or fatigue, weight loss and repeated infections. Multiple myeloma is hard to cure. Treatments include chemotherapy, stem cell transplantation and radiation. The prognosis is poor.
How do I know if I have multiple myeloma and what are the symptoms of multiple myeloma?
Early multiple myeloma does not have any symptoms. As the tumor grows larger, people may notice one or more of the following symptoms:
- Bone pain
- Broken bones
- Numbness and/or muscle weakness
- Confusion
- Dizziness
- Edema in legs
Other health problems may also cause these symptoms. Only a doctor can tell for sure. A person with any of these symptoms should tell the doctor so that the problems can be diagnosed and treated as early as possible.
Who is at risk for multiple myeloma?
While the exact cause of multiple myeloma is not known, clinical data has suggested that the development of multiple myeloma is related to several factors.
- Age: Age is the biggest risk factor for multiple myeloma. Most cases are found in people older than 65.
- Plasma cell diseases: Studies show patients with other plasma cell diseases will develop multiple myeloma later.
- Radiation exposure: Cases reports demonstrate exposure to radiation may increase the risk of multiple myeloma.
- Exposure on oil-related industries: Some studies suggest that workers in some oil-related industries may be at a higher risk.
- Family history: Some data suggest multiple myeloma seems to run in some families. But most patients have no other relatives with the disease.
- Life-style: A study by the American Cancer Society found that being overweight increases a person's risk of developing multiple myeloma.
- Race: Epidemiological data show multiple myeloma is almost twice as common among black Americans as white Americans.
- Gender: Men are slightly more likely to get multiple myeloma than women.
How to know you have multiple myeloma?
- Quantitative immunoglobulins: In multiple myeloma, the level of one type may be high while the others are low.
- Blood biochemistry tests: This test may show the high level of calcium in the blood and impairs of renal function.
- Blood test: The blood test result of patients with multiple myeloma may show low level of all blood cells.
- Bone marrow biopsy: This is the most valuable test for diagnosis of multiple myeloma. During this procedure, the doctor uses a needle to remove some solid bone and some bone marrow at the back of the pelvic bone.
- Bone x-rays: By this test, the doctors can identify bone damage caused by the myeloma cells.
- Computed tomography (CT) scan: CT scans can help to tell if the bones have been damaged by myeloma.
- Magnetic resonance imaging (MRI): An MRI uses magnetic fields but it is a different type of image than what is produced by computed tomography (CT) and produces detailed images of the body. Like computed tomography (CT), a contrast agent may be injected into a patient’s vein to create a better picture. MRI scans are very helpful in looking at bones, the brain, and the spinal cord damaged by the myeloma cells.
- Positron emission tomography (PET) scan: When doing this test, a small amount of a radioactive medium is injected into your body and absorbed by the organs or tissues. This radioactive substance gives off energy which in turn is used to produce the images. PET can provide more helpful information than either CT or MRI scans. It is useful to see if the cancer has spread to the lymph nodes and it is also useful for your doctor to locate where the cancer has spread.
When to seek urgent medical care?
Call your health care provider if symptoms of multiple myeloma develop. If you experience either of the following symptoms, seeking urgent medical care as soon as possible:
Treatment options
Diseases with similar symptoms
Where to find medical care for multiple myeloma?
Directions to Hospitals Treating multiple myeloma
Prevention of multiple myeloma
For the exact cause is not clear, the preventive measure is unknown.
What to expect (Outook/Prognosis)?
Copyleft Sources
http://www.nlm.nih.gov/medlineplus/multiplemyeloma.html