Endocarditis pathology

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Associate Editor-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Pathologic Findings in the Acute Phase

The valve and the surrounding anatomy should be carefully inspected for the following complications:

Fistula
Perforation
Prosthetic dehiscence
Aneurysm
Vegetations
Valve ulcers or erosions
Rupture of chordaes
Endocardial jet lesions
Flail leaflets or cusps
Abcess formation (annular and ring)

Pathologic Findings in the Chronic Phase

Perforations
Nodular calcifications
Tissue defects of valves
Fibrosis of valves

Gross Pathology of Endocarditis

Images shown in this section are courtesy of Professor Peter G. Anderson D.V.M. PhD, and published with permission.

Thrombotic Nonbacterial Endocarditis: (Gross) An excellent example of thrombi on aortic valve.
Thrombotic Nonbacterial Endocarditis: (Gross) Mitral valve lesion appears that have been present for at least several days.

Bacterial Endocarditis: (Gross) Perforated aortic valve cusp is shown.
Thrombotic Nonbacterial Endocarditis: (Gross) Aortic valve with two small vegetations.

Thrombotic Nonbacterial Endocarditis: (Gross) Mitral valve thrombi in chorda.
(Gross) A very good example of focal necrotizing lesions in distal portion of digit associated with bacterial endocarditis

Bacterial Endocarditis: (Gross) A lesion on non-coronary cusp of aortic valve.
Bacterial Endocarditis: (Gross) An excellent view of mitral scarring due to rheumatic fever healing infectious lesion.

Bacterial Endocarditis: (Gross) Aortic valve prosthesis ring infection extending into left atrium.
Bacterial Endocarditis: (Gross) An excellent close-up view of mitral valve vegetations

Bacterial Endocarditis: (Gross) vegetations on mitral valve and left atrial endocardium due to actinomycosis
Bacterial Endocarditis: (Gross) An excellent image of vegetation on aortic valve

Bacterial Endocarditis: (Gross) An excellent image of vegetations on mitral valve evidence of rheumatic scarring
Thrombotic Nonbacterial Endocarditis: (Gross) Mitral valve, an excellent example

Thrombotic Nonbacterial Endocarditis: (Gross) Mitral valve: an excellent image, identical to acute rheumatic lesion
Verrucous Nonbacterial Endocarditis: (Gross) An excellent example of an infant heart

Purpura of cerebrum, cerebellum and brain stem in 36 years old female with Cushing syndrome and bacterial endocarditis caused by Staphylococcus aureus
Spleen infarct: (Gross) A typical small infarct with necrotic central portion (originated from infected marantic endocarditis on aortic and mitral valves)

Kidney infarct: (Gross) A natural color close-up and excellent image of yellow infarct marantic endocarditis on aortic and mitral valves
Thrombotic Nonbacterial Endocarditis Infected: (Gross) Natural color of pulmonary valve. An excellent example of patient with multiple myeloma

Thrombotic Non Bacterial Endocarditis: (Gross) Natural color of pulmonary valve.
Thrombotic Non Bacterial Endocarditis: (Gross) Natural color and good example of tricuspid valve lesions