Subvalvular aortic stenosis

WikiDoc Resources for Subvalvular aortic stenosis
Articles
Most recent articles on Subvalvular aortic stenosis Most cited articles on Subvalvular aortic stenosis Review articles on Subvalvular aortic stenosis Articles on Subvalvular aortic stenosis in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Subvalvular aortic stenosis Images of Subvalvular aortic stenosis Photos of Subvalvular aortic stenosis Podcasts & MP3s on Subvalvular aortic stenosis Videos on Subvalvular aortic stenosis
Evidence Based Medicine
Cochrane Collaboration on Subvalvular aortic stenosis Bandolier on Subvalvular aortic stenosis TRIP on Subvalvular aortic stenosis
Clinical Trials
Ongoing Trials on Subvalvular aortic stenosis at Clinical Trials.gov Trial results on Subvalvular aortic stenosis Clinical Trials on Subvalvular aortic stenosis at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Subvalvular aortic stenosis NICE Guidance on Subvalvular aortic stenosis NHS PRODIGY Guidance FDA on Subvalvular aortic stenosis CDC on Subvalvular aortic stenosis
Books
Books on Subvalvular aortic stenosis
News
Subvalvular aortic stenosis in the news Be alerted to news on Subvalvular aortic stenosis News trends on Subvalvular aortic stenosis
Commentary
Blogs on Subvalvular aortic stenosis
Definitions
Definitions of Subvalvular aortic stenosis
Patient Resources / Community
Patient resources on Subvalvular aortic stenosis Discussion groups on Subvalvular aortic stenosis Patient Handouts on Subvalvular aortic stenosis Directions to Hospitals Treating Subvalvular aortic stenosis Risk calculators and risk factors for Subvalvular aortic stenosis
Healthcare Provider Resources
Symptoms of Subvalvular aortic stenosis Causes & Risk Factors for Subvalvular aortic stenosis Diagnostic studies for Subvalvular aortic stenosis Treatment of Subvalvular aortic stenosis
Continuing Medical Education (CME)
CME Programs on Subvalvular aortic stenosis
International
Subvalvular aortic stenosis en Espanol Subvalvular aortic stenosis en Francais
Business
Subvalvular aortic stenosis in the Marketplace Patents on Subvalvular aortic stenosis
Experimental / Informatics
List of terms related to Subvalvular aortic stenosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Associate Editors-In-Chief: Claudia P. Hochberg, M.D. [2]; Abdul-Rahman Arabi, M.D. [3]; Keri Shafer, M.D. [4]

Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [5] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

Epidemiology and Demographics

Aortic subvalvular stenosis is the second most common level of congenital obtruction of LV outflow, located just beneath the aortic valve and occurs in 8-30% of all forms of left ventricular outflow tract obstruction. IHSS is not present at birth and is not considered a congenital lesion.

The lesion is caused by accumulation of fibrous elastic tissue which most often

Anatomy

There are several varieties of Congenital Aortic Subvalvular Stenosis (or subaortic stenosis):

1. Membranous: A fixed localized membrane 0.5 to 2 cm below the level of the aortic valve and attached to the septum and the base of the anterior mitral leaflet.
2. Fibromuscular:
   • More commonly there is a fibromuscular membrane or tunnel with a significant muscular component which can sometimes be hard to distinguish from IHSS. This is a more severe form and is often associated with a small aortic root.
   • Associated aortic insufficiency (AI) is often present due to the high speed jet of blood through the aortic cusps resulting in fibrosis and retraction.
3. Congenital anomalies of the mitral valve:
   • Attachment to ventricular septum of accessory chordae from anterior mitral leaflet
   • Redundant AV valve tissue causing subaortic obstruction.
4. Aneurysm of the membranous ventricular septum

Clinical Features

• Similar to that of valvular aortic stenosis.
• AI more common in this form (50 to 75% of patients).
• Symptoms begin in infancy or early adulthood.