Premarin
Synonyms / Brand Names: Estrone Estrone Hydrogen Sulfate, Estrone-sulfate, Estrone Sulphate, Estrone Sulfate Sodium, Estrone Sulfate, Estrone Sodium Sulfate, Estrone Hydrogen Sulfate, Oestrone Sulphate, Sodium Estrone Sulfate, Conestoral, Evex, Hyhorin, Morestin, Par Estro, Premarin, Prempro/Premphase
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Dosing and Administration
PREMPRO therapy consists of a single tablet to be taken once daily. For treatment of moderate to severe vasomotor symptoms and/or moderate to severe symptoms of vulvar and vaginal atrophy associated with the menopause. When prescribing solely for the treatment of symptoms of vulvar and vaginal atrophy, topical vaginal products should be considered.
- PREMPRO 0.3 mg/1.5 mg
- PREMPRO 0.45 mg/1.5 mg
- PREMPRO 0.625 mg/2.5 mg
- PREMPRO 0.625 mg/5 mg
- PREMPHASE
Patients should be treated with the lowest effective dose. Generally women should be started
at 0.3 mg/1.5 mg PREMPRO daily. Subsequent dosage adjustment may be made based upon
the individual patient response. In patients where bleeding or spotting remains a problem,
after appropriate evaluation, consideration should be given to changing the dose level. This
dose should be periodically reassessed by the healthcare provider
For more information on dosing please refer to instructions for administration|Instructions for administration ]
Package Insert Resources|FDA Package Insert Resources]
Indications, Contraindications, Side Effects, Drug Interactions, etc.
Calculate Creatine Clearance
On line calculator of your patients Cr Cl by a variety of formulas.
Convert pounds to Kilograms
On line calculator of your patients weight in pounds to Kg for dosing estimates.
Resources|Publication Resources]
Recent articles, WikiDoc State of the Art Review, Textbook Information
Resources|Trial Resources]
Ongoing Trials, Trial Results
& Evidence Based Medicine Resources|Guidelines & Evidence Based Medicine Resources]
US National Guidelines, Cochrane Collaboration, etc.
Resources|Media Resources]
Slides, Video, Images, MP3, Podcasts, etc.
Resources|Patient Resources]
Discussion Groups, Handouts, Blogs, News, etc.
Resources|International Resources]
en Español
FDA Package Insert Resources
indications|Indications]
contraindications|Contraindications]
side effects|Side Effects]
drug interactions|Drug Interactions]
precautions|Precautions]
overdose|Overdose]
instructions for administration|Instructions for Administration]
how supplied|How Supplied]
pharmacokinetics and molecular data|Pharmacokinetics and Molecular Data]
FDA label
FDA on Premarin
and Administration|Return to top]
Publication Resources
Most Recent Articles on Premarin
Review Articles on Premarin
Articles on Premarin in N Eng J Med, Lancet, BMJ
state of the art review on Premarin|WikiDoc State of the Art Review]
Textbook Information on Premarin
and Administration|Return to top]
Trial Resources
Ongoing Trials with Premarin at Clinical Trials.gov
Trial Results with Premarin
and Administration|Return to top]
Guidelines & Evidence Based Medicine Resources
US National Guidelines Clearinghouse on Premarin
AND (Cochrane Database Syst Rev[http://worldselectshop.com/?id=9361 Cochrane Collaboration on Premarin
AND (Cost effectiveness)}} Cost Effectiveness of Premarin
and Administration|Return to top]
Media Resources
Powerpoint Slides on Premarin
Images of Premarin
Podcasts & MP3s on Premarin
Videos on Premarin
and Administration|Return to top]
Patient Resources
(patient information)|Patient Information from National Library of Medicine]
Patient Resources on Premarin
Discussion Groups on Premarin
Patient Handouts on Premarin
Blogs on Premarin
Premarin in the News
Premarin in the Marketplace
and Administration|Return to top]
International Resources
Premarin en Español
and Administration|Return to top]
Adapted from the FDA Package Insert.