Osteosarcoma
Osteosarcoma | |
ICD-10 | C40-C41 |
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ICD-9 | 170 |
ICD-O: | Template:ICDO |
OMIM | 259500 |
DiseasesDB | 9392 |
MedlinePlus | 001650 |
MeSH | D012516 |
Osteosarcoma Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Osteosarcoma On the Web |
American Roentgen Ray Society Images of Osteosarcoma |
For patient information click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [3] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
Overview
Historical Perspective
Pathophysiology
Epidemiology & Demographics
Risk Factors
Screening
Causes
Differentiating Osteosarcoma
Complications & Prognosis
Diagnosis
History and Symptoms | Physical Examination | Staging | Laboratory tests | Electrocardiogram | X Rays | CT | MRI Echocardiography or Ultrasound | Other images | Alternative diagnostics
Treatment
Medical therapy | Surgical options | Primary prevention | Secondary prevention | Financial costs | Future therapies
Case Examples
Case #1
Clinical Summary
This 14-year-old white male first experienced mild pain in the left knee after playing baseball, approximately two months prior to admission. The pain persisted in an intermittent fashion, and was described as being somewhat worse at night. Approximately two weeks prior to admission, the pain increased significantly and was accompanied by marked swelling and loss of considerable motion of the knee joint. These symptoms were accompanied by a history of decreased appetite, lethargy, and a 10-pound weight loss. On physical examination, the left knee was enlarged diffusely, firm, and non-tender. Following biopsy, the patient was subjected to surgical removal of the distal femur and knee with placement of a prosthetic knee joint and bone grafts.
Autopsy Findings
The distal diaphysis of the femur and adjacent soft tissues were involved in a 15 x 10 x 10-cm mass. The cut surface of the mass was fleshy white, with focal areas of hemorrhage.
Pathological Findings
References
Additional Resources
- James, H. (1979). Promises in the Dark. New York: Bantam Books. ISBN 0-553-13453-1. Story of a young girl's osteosarcoma fight and its effect on her relationship with her boyfriend
- Trottier, Maxine (2005). Terry Fox: A Story of Hope. Markham, Ont: Scholastic Canada. ISBN 0-439-94888-6. About Terry Fox and his quest to raise $25 million for cancer research by running across Canada on his prosthetic leg. Also The Terry Fox Story, a 1983 movie.
- Belshaw, Sheila M. (2001). Fly With a Miracle. Denor Press. ISBN 0 9526056 7 8.
External links
- Superior Survivial Seen with Osteosarcoma 2004
- Osteosarcoma: A Multidisciplinary Approach to Diagnosis and Treatment
- http://www.emedicine.com/PED/topic1684.htm
- http://www.mayoclinic.org/osteosarcoma/index.html
- Support Group and Information for people with osteosarcoma
- Treatment Information from U.S. National Cancer Institute
- Osteosarcoma by Peter Buecker, MD and Mark Gebhardt, MD
- Green Drakkoman Foundation to assist Warriors of Rare Childhood Cancers
Acknowledgements
The content on this page was first contributed by: C. Michael Gibson M.S., M.D.
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