Mononucleosis natural history
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Prognosis
Fatalities from mononucleosis are extremely rare in developed nations. Potential mortal complications include splenic rupture, bacterial superinfections, hepatic failure and the development of viral myocarditis.
Complications
Hematological
Neurological
- Cranial nerve palsies (Bell’s palsy)
- Encephalitis
Hepatology
Cardiology
Respiratory
- Airway obstruction (adenopathy)
Non-fatal compliactions
Uncommon, nonfatal complications exist, including various forms of CNS and hematological affection:
- CNS: Meningitis, encephalitis, hemiplegia and transverse myelitis. EBV infection has also been proposed as a risk factor for the development of multiple sclerosis (MS)[1], but this has not been affirmed.
- Hematologic: EBV can cause autoimmune hemolytic anemia (direct Coombs test is positive) and various cytopenias.
References
- ↑ Ascherio A, Munger KL (2007). "Environmental risk factors for multiple sclerosis. Part I: the role of infection". Ann. Neurol. 61 (4): 288–99. doi:10.1002/ana.21117. PMID 17444504.