Cardiac amyloidosis physical examination
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor: Cafer Zorkun, M.D., Ph.D. [2]; Lakshmi Gopalakrishnan, M.B.B.S. [3]
Overview
Cardiac amyloidosis is difficult to diagnose. The findings from an examination are not specific and may indicate enlargement of the heart and fluid retention in the lungs.
Signs
- Common signs:
- The blood pressure may be low or may drop when rising to a standing position (orthostatic hypotension). Orthostatic hypotension is typical especially in kidney involvement.
- Typical physical findings specific for cardiac amyloidosis:
- Auscultation may reveal rales, heart murmurs, and/or other pathologic heart sounds.
References
- ↑ Rapezzi C, Perugini E, Salvi F, Grigioni F, Riva L, Cooke RM, Ferlini A, Rimessi P, Bacchi-Reggiani L, Ciliberti P, Pastorelli F, Leone O, Bartolomei I, Pinna AD, Arpesella G, Branzi A (2006). "Phenotypic and genotypic heterogeneity in transthyretin-related cardiac amyloidosis: towards tailoring of therapeutic strategies?". Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 13 (3): 143–53. doi:10.1080/13506120600877136. PMID 17062380. Retrieved 2012-02-13. Unknown parameter
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