Cellulitis pathophysiology
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], “Associate Editor(s)-In-Chief:” Aditya Govindavarjhulla, M.B.B.S.
Overview
Cellulitis results in activation of the body's inflammatory response mechanisms. When the immune system cannot respond adequately, it can spread systemically through the blood stream.
Pathophysiology
Microorganisms gain access into the layers of the skin through the discontinuities. Body responds to these microbes as a foreign elements in its system and causes an inflammatory response. This leads to redness, swelling, pain and itching of the area involved. It is a local infection leading to inflammation of the area. With competent immune system , it limits the spread of the infection. If immune system fails to curb the infection it gets systemic by spreading into the adjacent areas finally entering the blood stream(Bacteremia).