Beta-actin

Actin, beta
File:PBB Protein ACTB image.jpg PDB rendering based on 1atn.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1atn​, 1c0f​, 1c0g​, 1d4x​, 1dej​, 1eqy​, 1esv​, 1h1v​, 1hlu​, 1ijj​, 1j6z​, 1kxp​, 1lcu​, 1lot​, 1m8q​, 1ma9​, 1mdu​, 1mvw​, 1nlv​, 1nm1​, 1nmd​, 1nwk​, 1o18​, 1o19​, 1o1a​, 1o1b​, 1o1c​, 1o1d​, 1o1e​, 1o1f​, 1o1g​, 1p8z​, 1qz5​, 1qz6​, 1rdw​, 1rfq​, 1rgi​, 1s22​, 1sqk​, 1t44​, 1wua​, 1y64​, 1yxq​, 2a3z​, 2a40​, 2a41​, 2a42​, 2a5x​, 2asm​, 2aso​, 2asp​, 2btf​, 2d1k​, 2ff3​, 2ff6​, 2fxu​, 2gwj​, 2gwk​, 2hf3​, 2hf4​, 2hmp​, 2oan​, 2q1n​, 2q31​, 2q36​
Identifiers
Symbols	ACTB ; PS1TP5BP1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 74383
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Beta-actin (gene name ACTB) is one of six different actin isoforms which have been identified in humans. This is one of the two nonmuscle cytoskeletal actins. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus.

Further reading

• Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease". Folia Biol. (Praha). 42 (5): 227–30. PMID 8997639.
• Gunning P, Weinberger R, Jeffrey P (1997). "Actin and tropomyosin isoforms in morphogenesis". Anat. Embryol. 195 (4): 311–5. PMID 9108196.CS1 maint: Multiple names: authors list (link)
• Kimura T, Hashimoto I, Nishikawa M, Fujisawa JI (1997). "A role for Rev in the association of HIV-1 gag mRNA with cytoskeletal beta-actin and viral protein expression". Biochimie. 78 (11–12): 1075–80. PMID 9150887.CS1 maint: Multiple names: authors list (link)
• Szentirmay MN, Sawadogo M (2000). "Spatial organization of RNA polymerase II transcription in the nucleus". Nucleic Acids Res. 28 (10): 2019–25. PMID 10773068.
• Anderson JL, Hope TJ (2005). "HIV accessory proteins and surviving the host cell". Current HIV/AIDS reports. 1 (1): 47–53. PMID 16091223.
• Pederson T, Aebi U (2006). "Nuclear actin extends, with no contraction in sight". Mol. Biol. Cell. 16 (11): 5055–60. doi:10.1091/mbc.E05-07-0656. PMID 16148048.

See also

• Actin
• ACTA1