Meningitis
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Meningitis Main Page |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2], Prashanth Saddala M.B.B.S
Synonyms and keywords: Leptomeningitis
Overview
Historical Perspective
Classification
Based on time course and CSF profile meningitis is classified into[1]:
- Acute septic and aseptic meningitis
- Recurrent meningitis
- Chronic meningitis
Meningitis can also be classified based on the cause :
- Bacterial meningitis
- Viral meningitis
- Fungal meningitis
- Parasitic meningitis
- Non infectious meningitis
Pathophysiology
Causes
Differentiating Meningitis from other Diseases
- Brain abcess - Brain abcess is a focal infection of the brain parenchyma commonly caused by bacteria, fungal and parasitic pathogens. Imaging and neurosurgical aspiration is required for is differentiation in addition to CSF profile.
- Encepahlitis - Encephatlitis is the inflammation of brain. Meningitis can itself cause encephalitis and is called meningoencephalitis. The symptoms appear gradually in encephalitis but occur abruptly in meningitis.
- Delirium tremens - Delirium tremens and alcohol withdrawal should be differentiated from meningitis especially when present with confusion and fever. Both the conditions can coexist.
- Brain tumour - Brain tumours can simulate purulent meningitis with symptoms fever, signs of meningeal irritation and marked CSF pleocytosis. Irritation of leptomeninges by tumour and its breakdown products causes these symptoms[2]. Determination of creatine kinase BB and carcinoembryonic antigen helps in differentiating.[3]
- Subarachnoid hemorrhage - Subarachnoid hemorrhage also presents with severe headache, neck stiffness, nausea and vomiting like meningitis. It is a medical emergency. Imaging studies help in differentiating. Tubercular meningitis should ]be considered in the differential diagnosis in cases of nonaneurysmal subarachnoid hemorrhage.[4]
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms | Physical Examination | Laboratory Findings | CT | Lumbar Puncture | Other Imaging Findings | Other Diagnostic Studies
Treatment
Medical therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies
Case Studies
Related chapters
Template:Diseases of the nervous system
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- ↑ Coyle PK (1999). "Overview of acute and chronic meningitis". Neurol Clin. 17 (4): 691–710. PMID 10517924. Unknown parameter
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ignored (help) - ↑ Soffer D (1976). "Brain tumors simulating purulent meningitis". Eur. Neurol. 14 (3): 192–7. PMID 1278192.
- ↑ Terheggen HG (1985). "[CNS tumors with the clinical picture of meningitis]". Monatsschr Kinderheilkd (in German). 133 (1): 13–9. PMID 3883130. Unknown parameter
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ignored (help) - ↑ Yeh ST, Lee WJ, Lin HJ, Chen CY, Te AL, Lin HJ (2003). "Nonaneurysmal subarachnoid hemorrhage secondary to tuberculous meningitis: report of two cases". J Emerg Med. 25 (3): 265–70. PMID 14585453. Unknown parameter
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ignored (help)