Achlorhydria causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Causes

• Autoimmune disorders where there is antibody production against parietal cells which normally produce gastric acid.
• H2-receptor antagonists
• Proton pump inhibitors.
• Mucolipidosis (type IV).
• Helicobacter pylori infection which neutralizes and decreases secretion of gastric acid to aid its survival in the stomach.
• Pernicious anemia
• Atrophic gastritis
• VIPomas
• Stomach cancer.
• Radiation therapy involving the stomach.