DYNC1I1

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Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

Cytoplasmic dynein 1 intermediate chain 1 is a protein that in humans is encoded by the DYNC1I1 gene.

In melanocytic cells DYNC1I1 gene expression may be regulated by MITF.

Interactions

DYNC1I1 has been shown to interact with DYNLL1.

Further reading

• King SM, Dillman JF, Benashski SE, et al. (1997). "The mouse t-complex-encoded protein Tctex-1 is a light chain of brain cytoplasmic dynein". J. Biol. Chem. 271 (50): 32281–7. doi:10.1074/jbc.271.50.32281. PMID 8943288.
• Lo KW, Naisbitt S, Fan JS, et al. (2001). "The 8-kDa dynein light chain binds to its targets via a conserved (K/R)XTQT motif". J. Biol. Chem. 276 (17): 14059–66. doi:10.1074/jbc.M010320200. PMID 11148209.
• Horikawa I, Parker ES, Solomon GG, Barrett JC (2001). "Upregulation of the gene encoding a cytoplasmic dynein intermediate chain in senescent human cells". J. Cell. Biochem. 82 (3): 415–21. doi:10.1002/jcb.1169. PMID 11500918.
• Karki S, Ligon LA, DeSantis J, et al. (2002). "PLAC-24 is a cytoplasmic dynein-binding protein that is recruited to sites of cell-cell contact". Mol. Biol. Cell. 13 (5): 1722–34. doi:10.1091/mbc.02-02-0011. PMC 111139. PMID 12006665.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Ligon LA, Tokito M, Finklestein JM, et al. (2004). "A direct interaction between cytoplasmic dynein and kinesin I may coordinate motor activity". J. Biol. Chem. 279 (18): 19201–8. doi:10.1074/jbc.M313472200. PMID 14985359.
• Villacé P, Marión RM, Ortín J (2004). "The composition of Staufen-containing RNA granules from human cells indicates their role in the regulated transport and translation of messenger RNAs". Nucleic Acids Res. 32 (8): 2411–20. doi:10.1093/nar/gkh552. PMC 419443. PMID 15121898.
• Chuang JZ, Yeh TY, Bollati F, et al. (2005). "The dynein light chain Tctex-1 has a dynein-independent role in actin remodeling during neurite outgrowth". Dev. Cell. 9 (1): 75–86. doi:10.1016/j.devcel.2005.04.003. PMID 15992542.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.