Whipple's disease historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
Overview
Historical Perspective
It was first described by George Hoyt Whipple in 1907,[1][2] and it is commonly considered a gastrointestinal disorder.
Mnemonic
A mnemonic was developed to help keep track of the main features of Whipple's disease. The mnemonic is as follows:
W H I P P L E S
- Weight Loss
- Hyperpigmentation of the skin
- Infection with Tropheryma whipplei
- PAS positive granules in macrophage
- Polyarthritis
- Lymphadenopathy
- Enteric Involvement
- Steatorrhea
References
- ↑ Template:WhoNamedIt
- ↑ Whipple GH (1907). "A hitherto undescribed disease characterized anatomically by deposits of fat and fatty acid in the intestinal and mesenteric lymphatic tissues". Bull Johns Hopkins Hosp. 18: 382&ndash, 93.