Wilms' tumor epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Epidemiology and Demographics

Approximately 500 cases are diagnosed in the U.S. annually. The majority (75%) occur in otherwise normal children; a minority (25%) is associated with other developmental abnormalities.

It is more common among some siblings and twins, which suggests a possible genetic cause.

The disease occurs in about 1 out of 200,000 to 250,000 children. It usually strikes when a child is about 3 years old. It rarely develops after age 8.