Multiple myeloma history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
History and Symptoms
Early multiple myeloma does not have any symptoms. In as many as 30-40% cases the diagnosis may be incidental and is often diagnosed on routine blood screening. A rise in total protein levels without a concomitant rise in albumin levels must make the physician suspicious for a possibility of multiple myeloma. As the tumor grows larger, people may notice one or more of the following symptoms:
- Bone pain
- Pathological fractures
- Numbness and/or muscle weakness
- Confusion
- Dizziness
- Edema in legs
- Back pain, numbness, dysesthesias suggestive of spinal cord compression.
- Bleeding
- Recurrent infections