Multiple myeloma MRI

	Multiple myeloma Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The workup of suspected multiple myeloma includes a skeletal survey. Myeloma activity sometimes appear as "lytic lesions" (with local disappearance of normal bone due to resorption), and on the skull X-ray as "punched-out lesions" (pepper pot skull). Magnetic resonance imaging (MRI) is more sensitive than simple X-ray in the detection of lytic lesions, and may supersede skeletal survey, especially when vertebral disease is suspected.