21-hydroxylase deficiency epidemiology and demographics

Congenital adrenal hyperplasia due to 21-hydroxylase deficiency Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Epidemiology and Demographics

The incidence of 21-hydroxylase deficient CAH detectable in childhood is about 1 in 15,000 births. The severe salt-wasting form accounts for the majority of these cases, which is high enough that many states and countries routinely include it in mandated newborn screening tests. The incidence of simple virilizing CAH is about 1 in 60,000 children.