Von Willebrand disease history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
History
Symptoms
The various types of vWD present with varying degrees of bleeding tendency. In general patients with vWD mainly present with mucosa-associated bleeding and bleeding after surgery and trauma. This usually may manifest in the form of easy bruising, nosebleeds and bleeding gums. Women may experience heavy menstrual periods and blood loss during childbirth. Severe internal or joint bleeding is rare (which only occurs in type 3 vWD). To make a diagnosis, there is usually personal or family history of bleeding and laboratory evidence of defective von Willebrand factor, factor VIII, or both.