Gallbladder volvulus

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]

Synonyms and keywords: Torsion of gallbladder;

Overview

Volvulus is twisting of a non solid organ around its mesentric axis. Gallbladder volvullus is twisting or rotation of gall bladder along the axis of cystic duct and vascular pedicle(cystic artery).[1]

Historical Perspective

It was first described by Wendal in 1898.[2]

Pathophysiology

Torsion of gall bladder leads to occlusion of cystic duct and artery. This torsion can be complete (180o - 360o) or incomplete(< 180o). Incomplete torsion causes obstruction to bile duct and vascular supply may be spared. In complete obstruction both are compromised.[3] This occlusion leads to increase in bile in the lumen and decreased flow of blood to the organ. Increased pressure in the lumen with ischemia leads to acute inflammation causing surgical emergency.

Gross Pathology

  • Enlarged and distended gallbladder.
  • Torsion along the long axis of the peduncle.
  • Thick edematous wall with mucosal congestion.

Microscopic Pathology

  • Extensive necrosis of the wall
  • Findings may be similar to gangrenous cholecystitis due to severe ischemia.

Causes

Volvulus of gallbladder is known to be caused due to[4]

  • Inherent causes
    • Floating gallbladder
  • Acquired causes
    • Splanchnoptosis
    • Senile humpback
  • Physical causes
    • Sudden changes of intraperitoneal pressure
    • Sudden changes of body position
    • Hyperperistalsis of organs near the gallbladder
    • Defecation
    • Trauma to the abdomen

Epidemiology and Demographics

Over 500 cases have been documented since its description in 1898.[5]

Age

  • Few cases are reported in pediatric population.
  • 85% of the cases are reported in 60 - 80 age group.

Gender

  • There is a female preponderance for this condition.[6]
  • Female to male ratio is 3:1. [7]

Risk Factors

Risk factors for gallbladder volvulus include[8]

  • Hyperperistalsis
  • Scoliosis
  • Weight loss
  • Multiparity

Cholelithiasis as a risk factor is still uncertain.

Natural History, Complications and Prognosis

Complications

  • Acute perforation
  • Bilious peritonitis
  • Bowel adhesion's
  • Gallbladder necrosis
  • Gangrenous cholecystitis
  • Sepsis

Prognosis

  • It has favorable a prognosis due to early diagnosis and prompt treatment.
  • With immediate surgery the mortality rate is less than 5%. [9]

Diagnosis

History

A directed history should be obtained to ascertain

Symptoms

"Type symptom here" is pathognomonic of the "type disease name here".

"Type non specific symptoms" may be present.

Past Medical History

Family History

Social History

Occupational

Alcohol

The frequency and amount of alcohol consumption should be characterized.

Drug Use

Smoking

Allergies

Physical Examination

Appearance of the Patient

Vital Signs

Skin

Head

Eyes

Ear

Nose

Throat

Heart

Lungs

Abdomen

Extremities

Neurologic

Genitals

Other

Laboratory Findings

Electrolyte and Biomarker Studies

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

References

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