Actinomycosis medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Treatment for actinomycosis consists of antibiotics such as penicillin or amoxicillin for six to twelve months, as well as surgery if the disease is extensive.
Antimicrobial regimen
- Actinomyces species including A. israeli[1]
- Preferred regimen: Penicillin 3-4 MU IV q4h for 2-6 weeks THEN Penicillin V 2-4 g/day PO qid for 6-12 months
- Alternative regimen (1): Erythromycin 500-1000 mg IV q6h OR 500 mg PO qid
- Alternative regimen (2): Tetracyclin 500 mg PO qid
- Alternative regimen (3): Doxycycline 100 mg IV q12h OR 100 mg PO bid
- Alternative regimen (4): Clindamycin 900 mg IV q8h OR 300-450 mg PO qd
- Alternative regimen (5): Minocycline 100 mg IV q12h OR 100 mg PO bid
References
- ↑ Bennett, John (2015). Mandell, Douglas, and Bennett's principles and practice of infectious diseases. Philadelphia, PA: Elsevier/Saunders. ISBN 978-1455748013.
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