Lung abscess causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Causes
Conditions contributing to lung abscess
- Aspiration of oropharyngeal or gastric secretion
- Septic emboli
- Necrotizing pneumonia
- Vasculitis: Wegener's granulomatosis
- Necrotizing tumors: 8% to 18% are due to neoplasms across all age groups, higher in older people; primary squamous carcinoma of the lung is the commonest.
Organisms
In the post-antibiotic era pattern of frequency is changing. In older studies anerobes were found in upto 90% cases but they are much less frequent now[1].
- Anaerobic bacteria: Peptostreptococcus, Bacteroides, Fusobacterium species,
- Microaerophilic streptococcus : Streptococcus milleri
- Aerobic bacteria: Staphylococcus, Klebsiella, Haemophilus, Pseudomonas,Nocardia, Escheria coli, Streptococcus, Mycobacteria[2]
- Fungi: Candida, Aspergillus
- Parasites: Entamoeba histolytica
Reference
- ↑ Bartlett JG (2005). "The role of anaerobic bacteria in lung abscess". Clin. Infect. Dis. 40 (7): 923–5. doi:10.1086/428586. PMID 15824980.
- ↑ Hirshberg B, Sklair-Levi M, Nir-Paz R, Ben-Sira L, Krivoruk V, Kramer MR (1999). "Factors predicting mortality of patients with lung abscess". Chest. 115 (3): 746–50. PMID 10084487.